Carbimazole should be stopped temporarily at the time of administration of radio-iodine (to avoid thyroid crisis). Just a thought. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T 3 and T 4 Medical uses. I went from a size 8/10 to 14/16 and I understand completely how demoralising this is. I had thyrotoxicosis/Graves' disease twice and the dosage depending on others results to start with is 20mg carbimazole, with regular blood tests to see any changes and change do have to stay on the tablet for at least a year to make sure the thyroid is working ok. Don't stop carbimazole unless you are put on another thyroid medication otherwise graves will come back. Do you have any problems with your eyes? This means they can get a bit worked up when it's well outside range. Thyroid hormones control metabolic rate and thus a decrease in thyroid hormones will imply a decrease in metabolic rate … I have more energy, no palpitations, temperature controlled, hair grown back etc etc. The other drug acted on me the same way as Carbi and I had no alternative but Radio Iodine or surgery. At 16st and climbing (5'5" female) I am terrified of putting on more weight when I know I should be focused on loosing it. Carbi can cause several reactions. I now eat less than I did before but a much healthier diet. Reply (3) Report. I have been diagnosed with hyperthyroidism and was given Carbimazole as the long term medication. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Iodine treatment and total thyroid removal are not a solution and should be the last resort. Make new blood tests and maybe your future includes adding Levo to your daily routine (besides Carbi). I was on steroids and could do a thing because my heart was literally exhausted. Any side-effects that do occur are likely to be mild and wear off after a week or so. The most common adverse effects associated with carbimazole administration are gastrointestinal signs (Bucknell, 2000). Hi again. "i am taking 10mg of carbimazole daily for my hyperthyroism condition. I think part of the problem is that while I was very hyper, I could eat anything and not put on weight. I have today been diagnosed for the 2nd time with an overactive thyroid. I was diagnosed with hyperthyroidism at Easter and am seeing the endocrinologist tomorrow. Please don't even think about RAI or surgery its only a quick route to life long meds and a feeling of will I ever feel better being hypo. If you are putting weight on at that rate you are probably becoming underactive. But honestly I did feel better after a short while of starting medication. Eat smart, take supplements (if you need) and follow your thyroid every 4-6 months. Has anyone experienced anything similar or have any advice? Start studying side effects. The first was about 6 years ago and I was put on 25mg of Carbimazole a day. Hyperthyroidism can cause weight gain so stopping Carbimazole may not help anyway. If abnormal liver function is discovered, the treatment should be stopped. Feeling sick (nausea) Headache or feeling dizzy; Skin rashes; Itching; Stomach upset ; Painful joints; Hair thinning; Changes to your taste. I don’t eat wasted calories such as processed food and instead eat loads of veggie and fruit. My advice is please don’t use your carbimozole dose as a weight loss aid. Although the Carbizamole has made me generally feel a bit better already, I have put on a stone since first taking them. Hypothyroidism causes weight gain … I went totally gluten free a couple of years ago and have totally reduced my thyroid antibody levels. As Iv had this unpleasant experience twice with the gps refusing to believe me when I say I have a thyroid problem and them saying your tsh is fine so everything must be ok I had to fight to get the hospital, yes I ended up there to do a t3 and t4, t4 came back dangerously high at 95 when our hospital range is 12-22, so you can imagine the state I was in so Iv now opted for surgery which I know means medication for life. The problem is, your best chance of beating Graves' is to become euthyroid (within range) and stay there. Answered by Dr. Bhavin Patel: Stopping may cause: Stopping the medication may worsen your symptoms. unusual weight gain; upper right abdominal pain; yellow eyes or skin; Side effects not requiring immediate medical attention. Carbimazole inhibits thyroxine so if you have too much of it, I guess it could make you feel like your thyroid is underactive, which would explain the exhaustion you're feeling. Other side effects include:vomiting. i was diagnosed with HyperT around a month ago and at diagnosis had a T4 reading of 38.8. Carbimazole is used to treat hyperthyroidism. If so, it may be Thyroid Eye Disease which is made worse by RAI. Thyroidectomy or radioactive ablatement will make you hypothyroid and should be a last resort if remission fails and you can't restart Carbimazole. I had Graves in 2008 and unfortunately I developed the worst allergic reactions to Carbi and ended up in a hospital for some days under full-time observation... the worst experience ever (that is another story). Hi, Thank you your reply it sounds like we had very similar symptoms and you have experienced the same issues with endocrine, being either useless or just Ok, I'm pleased to hear that weight loss can be achieved but more importantly to stay a good healthy weight and eat a healthy diet makes me feel a bit more reassured, I'm just a little frustrated with endocrine as I seem to get different stories every time I see them, they have not really talked about my tsh levels but my gp is concerned as they are very low at 0.02 but I'm going to discuss this with endo tomorrow as have an appointment with them and hopefully I will get some answers from them, I don't understand how they can say I am stable on carbimazole if my tsh is clearly saying everything is not as it should be, Thank you so much for your help and advice. Go out there and look for a GP or Endo you can talk to and present your worries. And welcome to the club. The endo will use your current levels, plus possibly the graph from your previous tests to this one, to decide what dose of carbimazole you are on. TSH stands for 'thyroid stimulating hormone' - it tells the thyroid to create more hormones. At the time of diagnosis my thyroid was out of control. Since taking a long hard look at my exercise and diet habits I’ve lost half a stone and continue to lose weight and I’m now down to a size 12. Also if it is found that you do have Graves, having a thyroidectomy does not change that - you will still have Graves, which may manifest in other ways. I would think that the serious side effects of carbimazole are like most drugs, quite rare. Don't think about it now. The half-life may be prolonged due to the liver disorder. There were also quite a few months when I really wasn’t up toop much exercise, and it’s been difficult to get back into the habit. Carbimazole is used for hyperthyroidism and other conditions. Other side effects include: pruritus, speech disturbance, amblyopia, and xerostomia. Being hyperthyroid was not good for your body and it was damaging you internally in a multitude of ways - in ways you couldn’t see. 18-24 months off carbizole then same again. There is a serious risk of permanent heart damage and osteoporosis when hyperthyroidism is not treated. Hi, I have been diagnosed with hyperthyroidism and graves last year and since then I have put 2 stone on in less than a year, wondered if anyone has had the same issues , I'm on carbimazole. If besides the weight gain you are feeling well under Carbi, keep it going and feel the luck. Can someone tell me what are the side effects and will it cause weight gain? ), allergies, pre-existing diseases, and current health conditions (e.g. How much carbi are you on, when were your last tests, and do you have the results ? If the dose you are on has helped to control your thyroid hormone - please don’t play around with it. Ive been hypo for many years but on levothyroxine for two and am still gaining weight even thought i make sure I get daily exercise. Hypothyroidism causes weight gain in the majority of patients and many find Levothyroxine replacement for hypothyroidism causes extra weight gain and hair loss. Know Carbimazole uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for CARBIMAZOLE. The dose has to be well monitored and this medicine can not be used as means for weight loss. Its not the Carbimazole itself that makes you gain weight, it's the effect it has on your thyroid gland. Have they checked for antibodies it will tell you if you have graves or hashimios. Meaning, one DO NOT PLAY with drugs, especially a complicated one as Carbi. If you don't have Graves disease there is a good chance of permanent remission of hyperthyroidism after 9-18 months. how much weight will i gain on carbimazole ? While this can be treated relatively easily with levo, you're just as likely to find it difficult to lose weight while you're hypo, if not more so. Weight gain has been reported as one of the possible side effects. The last thing on earth I would do is mess with my carbimazole dose though. Carbimazole is used for Hyperthyroidism etc. i curtail this weight gain and even loose weight? Other side-effects you need to know about. Do you know what your B12, vitamin D, ferritin and folate levels are as well as your thyroid results and what are your antibodies like now? Weight gain could cause … This study showed that among 42 patients with Graves' disease that the average weight gain was around 12 pounds after starting Methimazole. If you don't have Graves disease there is a good chance of permanent remission of hyperthyroidism after 9-18 months. pregnancy, upcoming surgery, etc. So far, you've only mentioned weight gain. Can I just not willingly have the surgery/IRT immediately and get it overand done with? I am starting to consider to stop taking the medication as I really can't face it & just feel like I am replacing one health problem with another. A lot of people on Carbi eventually start taking some Levo. If you are slowly getting better results with carbimozole and have been fortunate not to develop Thyroid Eye Disease then you should continue with that. I'm 51 and work in the media. So essentially my choices were to deal with the weight gain, or start popping pills to manage the side effects … I have today been diagnosed for the 2nd time with an overactive thyroid. My hormones have now been under control for about 6 months and I have had to adjust to the fact that when I was hyper my body was burning calories at a falsely fast rate and so, now that it is slowed down I have to adjust to that. If you ask for a copy of your results tomorrow, and publish them together with your carbimazole dose, and where that has been left the same or reduced, we may be able to help you further. You may have to starting taking some Levo. There is a serious risk of permanent heart damage and osteoporosis when hyperthyroidism is not treated. Type: Prescribing and Technical Information (Add filter) I have been taking 75mcgs of T3 only for two and a half years. I don’t know though. Once diagnosed - I was on carbimozole and propranolol plus various treatments for the eye disease. A couple years have met a woman whose sister died from Carbi allergy (in Denmark). i started taking carbimazole for my... View answer Please dont think that removal of thyroid gland will magically make you feel better - you really will be exchanging one health condition for another as you will almost definitely become hypothyroid which brings its own problems (and you will not be able to go back from that point). It might be better to do that than to start messing around with your carbimazole. They prescribed synthroid. If you are hyper, it can be vanishingly low, and it may take a while to bounce back once you've started treatment. Remember you have a thyroid for a reason - with good consistent treatment, good diet, exercise and sleep you could stabilise it and get it to work for you not against you. Thank you for your response it has helped, I'm wondering whether I can play around with the dose a little to maybe speed up my metabolism a little and see if it helps. Help with weight gain/trouble losing from thyroid being out of whack. I almost died, I had a weird sort of paralysis/shock. I lost 2 stone during the graves period but have now put 3 on so weight gain is a possibility. Though less serious than other side effects, contact your doctor if any of these side effects become more bothersome or regularly occur. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. As long as you have your thyroid there remains the possibility to either stabilise it or for your Graves to go into remission. You dont want to mess up with it. Once Carbi becomes a problem then you have very few options. I have just started on gluten free in the hope that when I come off Carbizamole I can manage through lifestyle - diet and exercise. I read that you go back to your pre Graves weight. My son is hyper and painfully thin but put on weight on carbinizole but after a year has gone into remission and is ok now. Iv just been diagnosed with Graves’ disease, I feel this may be as a result of a stressful... diagnosed with hyperthyroidism and graves last year and since then I have put 2 stone on in less... avoid: uncooked veg, fluoride, soy, goitrogens, and take supplements including B complex, zinc,... been on 125mg levothyroxine since the day of my surgery. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Other side effects include: If you get any of the following side effects, they normally go away while you keep taking your medicine. Carbimazole tablets should be used with caution in patients with mild-moderate hepatic insufficiency. Hyperthyroidism causes weight loss!. In effect - a walking wreck! I'm worried about the side effects. Keep gaining weight and can't shift it help. I know, believe me, how weight gain can effect your self image - but your long term internal health outweighs this. Carbimazole :: Weight Gain. unexpected death of my husband last year. This is partly why I became exasperated with the endo dept at my hospital (Whittington - North London) as they kept tweaking and messing with my treatment - often only looking at half the picture whilst at the same time constantly saying they could whip out my thyroid, if I’d prefer.
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