Salted fish and inhalants as risk factors for nasopharyngeal carcinoma in Malaysian Chi… Despite salted fish being a classical risk factor of Nasopharyngeal Carcinoma (NPC), whether secular trends in salted fish consumption worldwide accounted for changes in NPC rates … Although rare in most other parts of the world, nasopharyngeal carcinoma (NPC) is a common malignancy in southern China, especially for the Cantonese who inhabit the central region of Guangdong Province (National Cancer Control Office, 1979; Yu et al., 1981).Ingestion of Chinese salted fish … Interviews with 100 cases and 100 controls indicated that salted fish … Please enable it to take advantage of the complete set of features! Do not smoke. Two hundred fifty incident cases of nasopharyngeal carcinoma under age 35 years in Hong Kong Chinese and an equal number of age- and sex-matched friend controls were interviewed. Cancer Res. Mothers of cases and controls were interviewed also, if available, to obtain information on childhood events concerning the study subjects. Consumption of Salted Fish and Other Risk Factors for Nasopharyngeal Carcinoma (NPC) in Tianjin, a Low-Risk Region for NPC in the People's Republic of China ... a Low-Risk Region for NPC in the People's Republic of China, JNCI: Journal of the National Cancer … Bakkalci D, Jia Y, Winter JR, Lewis JE, Taylor GS, Stagg HR. Armstrong RW, Imrey PB, Lye MS, Armstrong MJ, Yu MC, Sani S. Nasopharyngeal carcinoma in Malaysian Chinese: salted fish and other dietary exposures. Enter multiple addresses on separate lines or separate them with commas. Other likely causes include genetic susceptibility, consumption of food (in particular salted fish) containing … The Lancet Salted Fish and Nasopharyngeal Carcinoma PEOPLE of southern Chinese stock are unusually prone to nasopharyngeal carcinoma (NPC); South- East Asia is the principal area where this otherwise rare cancer is encountered. Risk factors for Epstein Barr virus-associated cancers: a systematic review, critical appraisal, and mapping of the epidemiological evidence. Novel Therapies Boosting T Cell Immunity in Epstein Barr Virus-Associated Nasopharyngeal Carcinoma. It is estimated that over 90% of young nasopharyngeal carcinoma cases in Hong Kong Chinese can be attributed to consumption of this food during childhood. Table 2 presents the relationship between dietary factors and NPC risk in the case-control dataset. People who were fed salt-cured fish when they were children, especially … Consumption of Cantonese-style salted fish during all time periods was significantly associated with nasopharyngeal carcinoma; the association was especially strong during childhood. Thank you for sharing this Cancer Research article. American Journal of Cancer ISSN: 0099-7374, Sign In to Email Alerts with your Email Address. Journal of Cancer Research ISSN: 0099-7013 Salted fish and inhalants as risk factors for nasopharyngeal carcinoma in Malaysian Chinese.  |  Smoking, alcohol consumption, and exposure to formaldehyde may also result in nasopharyngeal cancer. It occurs much more frequently in other parts of the world — specifically Southeast Asia.Nasopharyngeal carcinoma is difficult to detect early. Salted fish Salted fish – Bestofhealthline Chinese-style salted fish is labeled as potentially carcinogenic, and there are studies that link the consumption of this type of fish with nasopharyngeal cancer. These chemicals can damage DNA. Int J Cancer . National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Nasopharyngeal cancer was diagnosed and determined to be stage III (T3 N0: tumor ... salted-fish consumption in early childhood has been correlated with an unusually high incidence USA.gov. During … In a case-control study in Hong Kong, Geser et al. There was no association between nasopharyngeal carcinoma and tobacco, alcohol, or nasal ointments. 2018 Dec 4;19(1):15. doi: 10.1186/s12867-018-0116-5. Cantonese-style salted fish is generally made by drying the fish, using less salt and a higher degree of fermentation during the drying process than fish preserved (or salted… The relative risk for having Cantonese-style salted fish as one of the first solid foods during weaning was 7.5 (95% confidence limits, 3.9, 14.8), and the relative risk for consuming the food at least once a week compared to less than once a month at age 10 years was 37.7 (95% confidence limits, 14.1, 100.4). Certain foods might increase your risk of nasopharyngeal cancer. Cantonese-style Salted Fish as a Cause of Nasopharyngeal Carcinoma: Report of a Case-Control Study in Hong Kong, Clinical and Epidemiological Investigations, Association between Hepatitis C Virus Antibodies and Hepatocellular Carcinoma in Taiwan, Evaluation of Nontumorous Tissue Damage by Transcatheter Arterial Embolization for Hepatocellular Carcinoma, Comparison of Immunoscintigraphy and Computerized Tomography in Identifying Colorectal Cancer: Individual Lesion Analysis, Cancer Epidemiology, Biomarkers & Prevention. J Glob Health. High levels of one such nitrosamine, N … Since salted fish is traditionally eaten with rice, part of a staple diet for children, and poor populations of Southern China, these are the populations that are at highest risk of nasopharyngeal cancer. Armstrong RW, Imrey PB, Lye MS, Armstrong MJ, Yu MC, Sani S. Int J Epidemiol. Avoid taking excessive amounts of salted fish … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. There is strong evidence that eating high amounts of Cantonese-style salted fish increases the risk of nasopharyngeal cancer. NLM Soc Sci Med. 2019 Sep 1;149(9):1596-1605. doi: 10.1093/jn/nxz095. ↵2 To whom requests for reprints should be addressed. Cantonese-style salted fish and nasopharyngeal cancer Cantonese-style salted fish contains nitrosamines and nitrosamine precursors. 2020 Jun 16;21(12):4292. doi: 10.3390/ijms21124292. Then the EBV DNA may instruct the cells of the nasopharynx to divide and grow in an abnormal way. Salted fish added to soft rice, a mushy form of rice, is a common food fed to southern Chinese in the weaning and post-weaning period (34). Nasopharyngeal carcinoma in Malaysian Chinese: occupational exposures to particles, formaldehyde and heat. Renaud S, Lefebvre A, Mordon S, Moralès O, Delhem N. Int J Mol Sci.  |  Putera I, Ramadhan MG, Anindya S, Sutanto NR, Kurniawan A, Hosea FN, Safitri ED. Rates of nasopharyngeal cancer are high in areas where eating salt-cured foods, especially Chinese-style salted fish, is very common. NIH We conducted a case-control study of nasopharyngeal carcinoma among Malaysian Chinese to test inhalants, salted fish consumption, and use of tobacco, alcohol, and nasal ointments as risk factors for the disease. 1998;77:228–35. SALTED FISH AND NASOPHARYNGEAL CARCINOMA IN SOUTHERN CHINESE. How to Prevent? Multivariate analyses showed that IgA/VCA was the most important predictor of NPC, and salted fish … Barrett D, Ploner A, Chang ET, Liu Z, Zhang CX, Liu Q, Cai Y, Zhang Z, Chen G, Huang QH, Xie SH, Cao SM, Shao JY, Jia WH, Zheng Y, Liao J, Chen Y, Lin L, Ernberg I, Adami HO, Huang G, Zeng Y, Zeng YX, Ye W. J Nutr. Figure 8 RR (95% CI) of nasopharyngeal cancer for the highest compared with the lowest level of salted fish intake during adulthood .....39 Figure 9 Relative risk of nasopharyngeal cancer for 1 time per week increase of salted fish And on the list of Group 1 carcinogens is Chinese-style salted fish, which is known to cause nasopharyngeal cancer - which is related to the upper part of the throat behind the nose. Salted fish and other preserved foods presented the weakest risk factor associated with nasopharyngeal carcinoma in all life stages, and therefore may play a smaller role in nasopharyngeal carcinoma occurrence than … BMC Mol Biol. The two risk factors (consumption of salted fish and exposure to smoke and/or dust) were independent of each other. There, this cancer, affecting a silver-dollar-sized region at the back of the nose, is the leading cancer … Relationship Between Salted Fish Consumption and Nasopharyngeal Carcinoma: An Evidence-based Case Report. Previous Article HEALTH SCREENING IN RESIDENTIAL HOMES. Nasopharyngeal cancer is related to the race (the morbidity of the yellow is higher than that of the white) and genetic factor. 2000 Dec;29(6):991-8. doi: 10.1093/ije/29.6.991. These foods can be very high in nitrates and nitrites, which react with protein to form nitrosamines. 1983;17(20):1559-67. doi: 10.1016/0277-9536(83)90100-4. Eat plenty of fresh fruit, green vegetables and other sources of vitamin C to lower your cancer risk. Salted fish and nasopharyngeal carcinoma in Malaysia. Still, EBV infection rarely leads to NPC, so other factors probably play a role in whether or not it causes cancer. For instance, eating a diet high in salt-cured fish … ©1986 American Association for Cancer Research. Next Article FAMILIAL AND SPORADIC HODGKIN'S DISEASE … Copyright © 2021 by the American Association for Cancer Research. BMC Med Genomics. 1. Studies in Asia have shown that people who eat Chinese cured and salted fish are at an increased risk of nasopha… Very rarely does Epstein-Barr virus lead to cancer, which suggests a variety of influencing factors. We do not retain these email addresses. HHS Chinese-style salted fish intake in early life is considered an established risk factor for nasopharyngeal carcinoma (NPC). This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. However, results for adult intakes of salted fish and preserved … COVID-19 is an emerging, rapidly evolving situation. NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. Certain genetic inheritance of certain tissues may impact the immune system and cause nasopharyngeal cancer. Occupational exposure to smokes (relative risk, 6.0; p = 0.006) and to dusts (relative risk, 4.0; p less than 0.001) was also significantly associated with nasopharyngeal carcinoma. … Limit Your Consumption Of Salted Fish And Pickled Foods: Research shows that a diet rich in salted (or pickled) foods, particularly China-style salted fish, heightens the risk of nasopharyngeal cancer. We conducted a case-control study of nasopharyngeal carcinoma among Malaysian Chinese to test inhalants, salted fish consumption, and use of tobacco, alcohol, and nasal ointments as risk factors for the disease. Past and Recent Salted Fish and Preserved Food Intakes Are Weakly Associated with Nasopharyngeal Carcinoma Risk in Adults in Southern China. Matrix association region/scaffold attachment region (MAR/SAR) sequence: its vital role in mediating chromosome breakages in nasopharyngeal epithelial cells via oxidative stress-induced apoptosis. Would you like email updates of new search results? Diets very high in salt cured meats and fish or pickled foods are more common in some of these places. This site needs JavaScript to work properly. Interviews with 100 cases and 100 controls indicated that salted fish consumption during childhood was a significant risk factor (relative risk, 3.0; p = 0.04); childhood daily consumption of this food item compared to nonconsumption carried a relative risk of 17.4 [95% confidence interval = (2.7, 111.1)]. Clipboard, Search History, and several other advanced features are temporarily unavailable. Consumption of Cantonese-style salted fish during all time periods was significantly associated with nasopharyngeal carcinoma; the association was especially strong during childhood. Salted fish and nasopharyngeal carcinoma. Nasopharyngeal cancer is more common in parts of Asia and Northern Africa than it is in Europe. of salted fish and EBV was strongly associated with NPC, and more so than EBV or salted fish per se. Not so in southern China. Background Despite salted fish being a classical risk factor of Nasopharyngeal Carcinoma (NPC), whether secular trends in salted fish consumption worldwide accounted for changes in NPC rates … Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. 2020 Jun;10(1):010405. doi: 10.7189/jogh.10.010405. … Chinese salted fish linked to cancer In the United States and most developed countries, the incidence of nasopharyngeal carcinoma (NPC) has dwindled over the past 50 years. 3. Many cases of nasopharygeal cancer are not preventable, but taking these steps may help lower your risk of nasopharyngeal cancer: Avoid salt-cured fish and meats. Cancer Research Online ISSN: 1538-7445 That's probably because the nasopharynx isn't eas… Consumption of salted fish, salted vegetables and preserved/cured meat were all risk factors … (11) found a positive association between expo- sure to salted fish …  |  The diet rich in salted fish or meat also increase the risk of developing this cancer. Nasopharyngeal (nay-zoh-fuh-RIN-jee-ul) carcinoma is cancer that occurs in the nasopharynx, which is located behind your nose and above the back of your throat.Nasopharyngeal carcinoma is rare in the United States. 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